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Biogen Stays Steady As Alzheimer’s Programs Falter

 
• By Mary Jo Laffler

Still reeling from aducanumab’s failure in Phase III Alzheimer’s trial, Biogen management played up the company’s progress toward diversification and the promise of its pipeline. 

Risk Dial
Biogen's high-risk pipeline has investors concerned

During its 24 April earnings call, Biogen Inc. tried to redirect attention from the recent Phase III failure of its Alzheimer’s candidate aducanumab and onto the better-than-anticipated performance in the first quarter. But with a key patent for its blockbuster multiple sclerosis drug Tecfidera under challenge, competition coming for its spinal muscular atrophy treatment Spinraza and a high-risk pipeline, the pressure is on.

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AstraZeneca Logs Japan Growth Despite Price Cuts

 
• By Lisa Takagi

AstraZeneca logs growth in Japan despite a big reimbursement price cut for one of its top sellers and expects 40 approvals in the country over the next six years.

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The big pharma forecast a $400m expense this year related to tariffs, but those estimates only reflect medtech tariffs already announced, not potential pharma tariffs.

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More from Business

Japan’s Ciconia Seeks Academic Candidates To Hatch In Global Market

 
• By Lisa Takagi

Japanese incubator Ciconia has just started verifying its first drug candidate with a vision of building domestic startups with globally competitive assets.

Sanofi Licenses Bispecific Candidates From AI-Driven Earendil

 
• By Joseph Haas

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Finance Watch: Investors Push ESSA Pharma, Elevation Oncology To Wind Down

 
• By Mandy Jackson

Restructuring Edition: ESSA and Elevation are reviewing strategic alternatives after trial failures, but each has an investor urging them to liquidate. Also, Third Harmonic and Vincerx are winding down, while Keros and Tempest are assessing options, but Opthea and OPM are cutting jobs.