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On The Path To Regeneration: NovaGo’s New Approach To Stroke

 
• By Jo Shorthouse

Zurich University spin-off NovaGo Therapeutics is taking a regenerative approach to stroke, and with €10m funding from a series A round to proceed its preclinical asset into Phase I, it is hoping to be in the clinic within two years.

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NovaGo is hoping to prove CNS regeneration is possible and efficacious • Source: Shutterstock

Swiss start up, NovaGo Therapeutics, co-founded by Zurich University professor Martin Schwab and Neurimmune Holdings AG founder and president Roger Nitsch, is based on Schwab’s discovery of inhibitors of neurite growth which cause the absent regeneration of injured fiber tracts in the central nervous system.

It has since been demonstrated that blocking the most potent of those nerve fiber growth inhibitors, Nogo-A, led to regeneration...

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Capricor Gets Complete Response For DMD Cell Therapy

 
• By Joseph Haas

Seven weeks before its action date, Capricor got an FDA complete response for cell therapy deramiocel in DMD-related cardiomyopathy. It has a Phase III study nearing readout, though.

Concentra Picks Up Cargo In Latest Troubled Biotech Buyout

 
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The Kevin Tang-led firm will pay $4.38 per share for Cargo, which laid off most of its workforce following the failure of a Phase II CAR-T trial.

Stock Watch: US CAR-T And Vaccine Actions: Net Negative For Access

 
• By Andy Smith

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AbbVie Makes Big Autoimmune CAR-T Play With Capstan Acquisition

 
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Bluebird Builds Out Leadership Team Under Private Equity Ownership

 
• By Jessica Merrill

The gene therapy developer appointed a new president, chief medical officer and chief of staff following the closing of its acquisition by private equity firms Carlysle and SK Capital.

AbbVie Makes Big Autoimmune CAR-T Play With Capstan Acquisition

 
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Removal Of REMS For CAR-Ts Could Greatly Expand Their Reach

 
• By Alaric DeArment

The FDA eliminated REMS requirements for approved CAR-T cell therapies that have limited their availability, a move that could enable increased use in the community setting.