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AZ’s Calquence Hits Endpoint In Second CLL Phase III Study

 
• By Scrip Team

The results move AstraZeneca closer to challenging AbbVie and Johnson & Johnson’s blockbuster Imbruvica in the blood cancer market.

Cycling
Calquence in pursuit of Imbruvica • Source: Shutterstock

A Phase III trial of AstraZeneca PLC’s Calquence has met its primary endpoint, marking the second time in as many months that the drug has passed a pivotal test.

AstraZeneca secured rights to the BTK inhibitor in 2015 when it paid $2.5bn for a majority stake in Acerta...

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Boehringer Ingelheim Expects Two Key Approvals In Second Half Of 2025

 
• By Andrew McConaghie

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Memo Therapeutics Plans BK Virus Therapy Phase III Despite Trial Miss

 
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Pointing to data that show a benefit in reducing viral load and the histological signs of the infection, Memo says its drug, potravitug, could become the first therapy to treat BK polyomavirus in kidney transplant recipients.

AZ Poised To Bring Self-Administered C5 Inhibitor To Market

 
• By Jessica Merrill

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Leo Looks To Grow In US After Hand Eczema Cream Approval

 
• By Kevin Grogan

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More from R&D

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• By Jessica Merrill

Gefurulimab will give AstraZeneca a new option to compete against Argenx’s Vyvgart Hytrulo, which is available subcutaneously.

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Obesity Beyond GLP-1s: Amylins – The Next Frontier

 
• By Aakash Babu

In this series of articles, we look at different mechanisms of actions beyond GLP-1s that could determine the obesity drug landscape in the coming years. First on our list – amylin receptor agonists, which analysts expect to grow into a $50bn market opportunity.