Conatus Pharmaceuticals Inc. hung in and talked up the potential of future results as long as it could but finally conceded on 24 June that its pan-caspase inhibitor emricasan had demonstrated a lack of efficacy in multiple patient types in non-alcoholic steatohepatitis (NASH). The San Diego firm said it will wrap up its obligations related to emricasan with partner Novartis AG and consider its strategic alternatives going forward.
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