Evotec DNA Damage Response Spin-Out Aims For First IND-Ready Drug In 2022

Evotec’s chief science officer tells Scrip the German biotech is putting its cancer therapeutic program focused on DNA damage response into a new spin-off that aims to have an IND-ready drug in 2022.

Spin off
Breakpoint Therapeutics will develop DDR therapies discovered internally by Evotec • Source: Shutterstock

Evotec SE has spun off its DNA damage response (DDR) portfolio into a new company called Breakpoint Therapeutics whose mission is to develop first-in-class drugs that kill cancer cells by sabotaging their DNA repair machinery. It aims to get the first of those therapies into human clinical trials by 2022, according to the German biotech’s chief science officer.

The spin-off was financed by an early-stage funding round of €30m covered by a consortium comprising life sciences-focused investment firm...

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