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BMS Ready To Pounce On Non-Chemo Opportunity In Lung Cancer With Checkmate-227 Data

 
• By Joseph Haas

The Checkmate-227 results surprised with an OS benefit for Opdivo plus Yervoy in first-line NSCLC and a miss for the Opdivo-chemotherapy combination. Bristol reported a solid quarter, with growth for IO, Eliquis.

win-lose
In Checkmate-227, BMS posted a win and a loss

A split decision had been expected in Bristol-Myers Squibb Co.’s Checkmate-227 study testing Opdivo combination therapy in first-line, non-squamous non-small cell lung cancer, but the win for Opdivo with low-dose Yervoy was a surprise – and could possibly open up a needed edge in the NSCLC setting for BMS.

The Princeton, NJ-based pharma unveiled top-line data from the Phase III Checkmate-227 after the markets closed on 24 July, hours ahead of its second quarter earnings call the following morning. BMS reported a solid earnings quarter on 25 July, with several products besting consensus sales estimates, and had virtually nothing new to say about its pending but delayed merger with Celgene Corp

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