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Synthorx Throws THOR-707 Into Competitive IL-2 Space With HAMMER, Its First-Ever Clinical Trial

 
• By Mandy Jackson

Emerging Company Profile: This is the first human study for lead product candidate THOR-707 and for the company's Expanded Genetic Alphabet platform, starting with a recombinant IL-2 that's being tested in solid tumors.

Emerging Company Profile Regular column feature image Version 2

Synthorx Inc. is putting its Expanded Genetic Alphabet platform to test in the company's first-ever clinical trial, evaluating the recombinant interleukin-2 (IL-2) THOR-707 in patients with advanced or metastatic solid tumors in the Phase I/II HAMMER study, to see if its technology can deliver on a promise of highly specific, more effective and safer biologics for cancer and autoimmune diseases.

THOR-707 is the first candidate to enter the clinic for San Diego-based Synthorx based on technology developed by scientific founder Floyd Romesberg, formerly of The Scripps Research Institute and...

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