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Summit Looking To Secure Superiority Claim For Ridinilazole Over Vancomycin In C. Diff

 
• By Joseph Haas

Company’s Phase III program is attempting to replicate Phase II efficacy data showing superiority for curing Clostridium difficile infections and preventing recurrence, while also compiling health economics data.

Bacteria
Summit thinks narrow-spectrum therapy is the best way to fight C. diff infections

Summit Therapeutics PLC says the goal for its novel antibiotics is to “cure the patient and keep them cured.” Under that banner, the company's ridinilazole, its Phase III candidate for Clostridium difficile infections, is being positioned as a better therapeutic option than the broad-spectrum antibiotic vancomycin, because its narrow-spectrum effect targets C. diff imbalance while leaving the rest of a patient’s microbiome undisturbed, reducing the likelihood of infection recurrence.

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