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Genfit Thinks Intercept’s Lead In NASH Not As Wide As Perceived

 
• By Joseph Haas

Genfit believes elafibranor’s clean tolerability and safety profile may help narrow the gap between it and Intercept’s OCA, with safety questions delaying OCA’s entry to market. Part two of Scrip’s interview with Genfit’s CEO and COO.

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Genfit should be the second company to file an NDA in NASH

Genfit SA is positioned to bring the second drug to market in non-alcoholic steatohepatitis (NASH) behind Intercept Pharmaceuticals Inc.’s obeticholic acid (OCA), but some analysts have expressed little confidence in Genfit’s elafibranor because of initially poor data in a Phase II trial. New Genfit CEO Pascal Prigent and his team are fighting against that perception as they look forward to reporting data from the Phase III RESOLVE-IT trial early in 2020.

The Lille, France-based company has argued for years now that it will compete well with OCA in the unmet medical...

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