Mirati’s First KRAS Data Look At Least As Good As Amgen’s

The small biotech firm has traded higher in recent months based on Amgen’s AMG 510 results to date, and saw its share price soar based on initial efficacy data for MRTX849 in lung and colorectal cancers. 

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KRAS G12C mutations are found in 14% of non-small cell lung cancer tumors • Source: Shutterstock

Mirati Therapeutics Inc.’s first-in-human results for the KRAS G12C inhibitor MRTX849 appear to be at least as good as data disclosed to date for Amgen Inc.’s similarly targeted AMG 510 in lung and colorectal cancer patients with KRAS-expressing tumors that have G12C mutations, according to data presented on 28 October at an early stage research meeting hosted by the American Association for Cancer Research, the National Cancer Institute and the European Organisation for Research and Treatment of Cancer. 

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