Roll Over Yamanaka: Meet The Cell Therapy Company Bypassing iPSCs

Mogrify Flips Adult Cells Directly From State To State

Emerging Company Profile: Horizon Discovery’s former CEO Darrin Disley talks to Scrip about the importance of Mogrify’s revolutionary platform for converting cells into any state without the need to create stem cells and force them through evolutionary biology.

SC1910_Atlas_1061699825_1200.jpg
Mogrify Has Created An Atlas Of Cellular Reprogramming • Source: Shutterstock

With a big data-based platform technology that promises to circumvent some of the major challenges of developing and manufacturing cell therapies, Mogrify Ltd. emerged from stealth mode earlier this year. It recently completed a $16m initial close of its series A financing round which brought its total funding to date to just over $20m. It boasts Jane Osbourn, former VP, R&D at AstraZeneca PLC’s MedImmune LLC, as its chair, and Darrin Disley, former CEO of gene editing firm Horizon Discovery Group PLC, as its CEO.

Disley grew Horizon from a start-up in 2007 through IPO in 2014 to the £85m acquisition of Dharmacon from General Electric in 2017, before departing the company in February 2018, by which time it had a market capitalization of around £300m

Mogrify At A Glance

 Location: Cambridge, UK

R&D Focus: Cell therapy

Disease Area(s): Diverse

Founding Date: Incorporated in 2016, commercially active from February 2019

Founders: Julian Gough (MRC Laboratory of Molecular Biology, UK), Owen Rackham (Duke-NUS Medical School, Singapore), Jose Polo (Monash University, Australia)

Employees: 35 (and recruiting another 30 in 2019/2020)

More from R&D

Merck KGaA Braces For Volatility But Does Not Expect Europe To Budge On Pricing

 

Shares are hit as German conglomerate lowers revenue forecast.

Leo Roars To A Profit In Q1 As Adbry Grows In US

 
• By 

The Danish firm's atopic dermatitis drug is holding its own despite strong competition from Sanofi/Regeneron’s Dupixent.

Lundbeck Lifted By Leap In Migraine Therapy Sales

 
• By 

Vyepti revenues rise by nearly 70% in the first quarter.

‘Market Developments’ Persuade Galapagos To Rethink Spin-Off

 

CEO Paul Stoffels exits early to be succeeded by Henry Gosebruch, who will now consider ‘all options’ for the Belgian firm as it tries to claw back investor confidence.

More from Scrip