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Dengvaxia Beater? Promising But Mixed Results For Takeda’s Dengue Contender

Experts Await Additional Data Coming Soon

 
• By Ian Haydock

Long-anticipated findings for Japanese firm’s dengue vaccine show efficacy rates above its only rival, including in those not previously exposed to the virus, but results for different strains were mixed and experts are awaiting additional data due in the next few weeks.

Close-up of a mosquito sucking blood
Hopes Cautiously Rising Over New Dengue Vaccine • Source: Shutterstock

Takeda Pharmaceutical Co. Ltd.’s candidate vaccine for dengue, TAK-003, has shown “promising efficacy” in a major trial in endemic countries across Asia and Latin America, demonstrating protection against virologically-confirmed dengue - the primary endpoint - in children aged four to 16 years.

But while the preliminary results look generally to have bested the only other dengue vaccine on the market, Sanofi’s Dengvaxia, disease experts are holding out for longer-term results and

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