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Merck/Bayer's Vericiguat Could Bring A New Dynamic For Heart Failure

 
• By Jessica Merrill

The Phase III VICTORIA study evaluating the safety of the sGC stimulator met its primary endpoint.

Autumn red leaf with cut heart in a hand - Image
Vericiguat helped certain patients with chronic heart failure in a Phase III study • Source: Shutterstock

Merck & Co. Inc. and Bayer AG appear to have cleared a major hurdle with positive Phase III data in hand on its soluble guanylate cyclase (sGC) stimulator in development to treat patients with chronic heart failure with reduced ejection fraction (HFrEF). Merck announced on 18 November that the Phase III VICTORIA study evaluating the efficacy and safety of vericiguat met its primary endpoint.

The companies only released topline data from the trial, but said vericiguat reduced the risk of the composite endpoint in...

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Final Chance To Have Your Say: Take Scrip's Reader Survey This Week

 
• By Eleanor Malone

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Galapagos Expands Point-Of-Care CAR-T Study To The US

 
• By Andrew McConaghie

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• By Andrew McConaghie

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• By Andrew McConaghie

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• By Sushmita Panda

Study to add to safety and tolerability data for infused formulation and may help identify optimal dose for future pivotal trial.