Pfizer’s Vyndaqel Success Interfering With Alnylam's Plans

Blockbuster Status In Sight For Pfizer Drug

Alnylam wants to emulate success of Eylea and Revlimid in amyloidosis– but Pfizer could spoil the plan.

New York, July 19, 2016: Corporate lettering on the exterior of the Pfizer headquarters in Manhattan.

Alnylam Pharmaceuticals Inc. is banking on its drug Onpattro becoming the foundation stone for a multi-billion dollar franchise in amyloidosis – but the runaway success of Pfizer’s rival Vyndaqel could upset those plans.

Onpattro (patisiran) became the first-ever RNA interference (RNAi) therapy to reach the market in August 2018, licensed to treat polyneuropathy in patients with the rare life-limiting condition hATTR amyloidosis

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