AstraZeneca Likes Sound Of Silence's Science

UK Biotech Gets $80m Upfront

25 Mar 2020

The UK major is getting access to Silence's small interfering RNA (siRNA) platform while the London-based biotech is getting further validation of its technology and a considerable pile of cash.

AstraZeneca enters field of small interfering RNA • Source: Shutterstock

AstraZeneca PLC has inked a collaboration with Silence Therapeutics PLC to develop gene-silencing drugs for cardiovascular, renal, metabolic and respiratory diseases, a deal that will transform the UK biotech's clinical and financial future.

Silence will be responsible for designing small interfering RNA (siRNA) molecules against gene targets initially against liver-based targets, as well as developing new delivery approaches to target the heart, lung...

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