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Moderna Stands Alone With Single-Antigen Approach To COVID-19 Vaccine

Targeting SARS-CoV-2 Spike Protein Is Sensible, Analyst Says

 
• By Joseph Haas

Moderna is pursuing a single-antigen strategy even though some of its mRNA vaccines have included multiple antigens; the SARS-CoV-2 spike protein likely provides the best antigen for developing immunity against the virus.

microbiologist with a tube of biological sample contaminated by Coronavirus with label Covid-19 / doctor in the laboratory with a biological tube for analysis and sampling of Covid-19 infectious disea
Moderna likely will require manufacturing partners if its COVID-19 is viable

Although Moderna Inc. doesn’t yet have any marketed products, analysts are encouraged that the Cambridge, MA, firm that was first into the clinic with a vaccine for the novel coronavirus SARS-CoV-2 can succeed in developing a COVID-19 vaccine based on findings from its development of vaccines for other infectious diseases.

The company will be providing more details on its vaccines program overall, including the mRNA-1273 coronavirus vaccine, at a 14 April investor day, but SVB Leerink analyst Geoffrey Porges put...

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