Kyowa Kirin Goes Global With MEI’s PI3K Contender In $683m Deal

Japanese firm builds on existing alliance to gain most global rights to US company’s potential best-in-class drug for lymphoma and B-cell malignancies.

Leukemia
MEI Strikes Major Deal For Hematological Malignancy Molecule • Source: Shutterstock

Japan’s Kyowa Kirin Co. Ltd. has acquired rights in most global markets to MEI Pharma Inc.’s phosphatidylinositol 3-kinase (PI3K) delta inhibitor ME-401, a promising oral, once-daily candidate moving through clinical development in follicular lymphoma and B-cell malignancies.

The major deal builds on and expands a November 2018 license agreement between the firms for the molecule in the Japan market and will immediately give MEI $100m upfront in cash as well as an

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