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BMS's Zeposia Shines in Ulcerative Colitis Phase III Study

Success Augurs Well For S1P Drug Class in UC

 
• By Sten Stovall

BMS’s S1P receptor modulator met endpoints in a Phase III trial treating patients with moderate to severe ulcerative colitis, boosting the drug class’s prospects in that condition.    

Colitis
Other S1P investigative drugs in UC include Arena’s etrasimod • Source: Shutterstock

Having just launched Zeposia (ozanimod) as a treatment for relapsing forms of multiple sclerosis, Bristol-Myers Squibb Co. is now well-positioned for using the sphingosine-1-phosphate (S1P) receptor modulator to treat ulcerative colitis (UC) after it met both primary endpoints and key secondary goals in a Phase III study.

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