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New Pfizer/BioNTech COVID-19 Vaccine Data Confirm Prior Results, Show T-Cell Boost

 
• By Mandy Jackson

While data from small trials are difficult to compare, it appears that T-cell responses to BNT162b1 may be stronger than those reported so far for Moderna’s competing mRNA-based vaccine. 

Vaccination against the new Corona Virus SARS-CoV-2: A syringe being drawn up with SARS-CoV-2 vaccination.
Pfizer and BioNTech report results from a second Phase I/II study, which was conducted in Germany • Source: Shutterstock

Pfizer Inc. and BioNTech SE released Phase I/II results for their messenger RNA (mRNA)-based COVID-19 vaccine candidate BNT162b1, from a clinical trial conducted in Germany, that showed T-cell responses that may be stronger than those observed with a competing mRNA vaccine from Moderna, Inc. The data are also consistent with neutralizing antibody data reported previously from a US study.

Pfizer and BioNTech reported results on 20 July from 60 German trial participants, including 12 patients each injected with 1mcg,...

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