Roche Hit By Surprising Tecentriq Miss In TNBC

Has Improved Survival With Nab-Paclitaxel But Not With Paclitaxel

Tecentriq is the only checkpoint inhibitor to get approval for first-line TNBC but failure in a second study for that indication will encourage rival Merck & Co with Keytruda nearing approval.

Roche tower
Roche HQ: Will Swiss major rue IMpassion131 study miss? • Source: Shutterstock

Roche Holding AG’s dominance in immunotherapy for triple-negative breast cancer (TNBC) has been loosened on the surprising news that a combination of its PD-L1 inhibitor Tecentriq and paclitaxel has failed a late-stage trial.

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