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Catalyst's Firdapse Expansion To Myasthenia Gravis In Doubt, LEMS Launch Disrupted By COVID-19

 
• By Jessica Merrill
Wooden roadblock in nature
Catalyst's indication expansion strategy hits a roadblock • Source: Shutterstock

Catalyst Pharmaceuticals, Inc.'s plan to expand Firdapse (amifampridine phosphate) to a broader range of inherited neuromuscular disorders has stalled for a second time with a Phase III clinical trial failure in patients with anti-MuSK antibody-positive myasthenia gravis, following a failed clinical trial in another rare neuromuscular condition last year.

The company announced the latest study failure with its second quarter financial results on 11 August. It also reported the...

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