Anti-Aging Firm Unity Stumbles At First Major Hurdle

Hit By Lead Drug Failure In OA

Unity is set to drop its lead product based on its senescent cell science as it fails in a Phase II study in osteoarthritis of the knee. Focus switches to ophthalmic product.    

Leaves
Can Unity turn back time? • Source: Shutterstock

UNITY Biotechnology, Inc.’s lead product, UBX0101, has hit the buffers in a Phase II osteoarthritis trial, raising some concern over the viability of its anti-aging thesis.

The 183-patient study found no difference between the p53/MDM2 interaction inhibitor and placebo in patients with moderate-to-severe painful osteoarthritis (OA)...

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