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Onconova On The Edge After Phase III Rigosertib MDS Failure

Switch To Oral Version But Not For MDS

 
• By Alexandra Shimmings

Onconova’s lead product, rigosertib, has failed in a Phase III study in myelodysplastic syndromes, sending its share price tumbling by 66%.    

Myelodysplastic_Sydrome
Myelodysplastic Syndrome cells • Source: Shutterstock

Onconova Therapeutics, Inc.. is looking at an uncertain future following the failure of its lead product, intravenous rigosertib, in the Phase III INSPIRE trial in myelodysplastic syndromes.

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