Vaccinex, Inc.’s potentially disease-modifying therapy for Huntington’s disease missed its key endpoints in top-line data unveiled 22 September from the Phase II SIGNAL study, but the biotech thinks the novel drug offers potential in both Alzheimer’s disease and also later-stage Huntington’s patients than those included in the trial.
Vaccinex Sees Mixed Signals In Huntington’s Study
Pepinemab Missed Key Endpoints In Phase II Trial
However, Vaccinex sees possible efficacy for SEMA4D inhibition in later-stage Huntington’s as well as Alzheimer’s disease. Pepinemab is also being studied with Keytruda in head-and-neck cancer.
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