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Santhera Restructuring: Discontinues Lead DMD Candidate

Pursuing Financing Options

 
• By John Davis

Switzerland’s Santhera is to restructure its business and seek extra funding after the failure of Puldysa (idebenone) in a Phase III Duchenne muscular dystrophy study at interim analysis.  

Restructuring
• Source: Shutterstock

Santhera Pharmaceuticals is to restructure its business and is pursuing options to improve its cash resources after it decided to discontinue the development of its candidate, Puldysa (idebenone), for the treatment of Duchenne muscular dystrophy. 

An interim futility analysis indicated Puldysa would be unlikely to meet the primary endpoint of the Phase III SIDEROS study,...

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