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Novartis Advances Novel Kidney Disease Therapy Iptacopan

Data Suggest Promise For Lead Nephrology Asset

 
• By Alexandra Shimmings

Phase II results look good for one of the first-in-class product’s potential indications, C3 glomerulopathy. The product was highlighted late last year as an up-and-coming pipeline asset.    

Human Kidneys, 2d rendering
• Source: Shutterstock

Novartis AG’s most advanced nephrology pipeline asset, iptacopan (LNP023), has proven its mettle in a Phase II study in one of its potential indications, C3 glomerulopathy (C3G).

C3G is a severe form of primary glomerulonephritis, characterized by complement dysregulation, and the data come just weeks after Novartis secured an EU PRIME designation for

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