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Gilead’s Lenacapvir May Offer Twice-Yearly HIV Salvage Therapy

 
• By Joseph Haas

A first-in-class capsid inhibitor for HIV, lenacapavir has produced strong efficacy data for viral load reduction in treatment-experienced patients. The data measure up well against Viiv’s Rukobia, analyst says.

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Gilead's development plans for lenacapavir appear on track

Gilead Sciences, Inc. unveiled strong top-line efficacy data for lenacapavir, its first-in-class capsid inhibitor for HIV, on 18 November, potentially positioning the antiretroviral for approval as a long-acting therapy in multi-drug resistant, heavily treatment-experienced patients. But the bigger opportunities for Gilead with the capsid inhibitor are down the line in the general HIV treatment population, as well as prevention.

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