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SynOx Seeks Solution For TGCT With Roche Antibody

Series A Raises €37m

 
• By Kevin Grogan

The UK's Celleron has attracted a "blue chip suite of investors" to an Irish-domiciled spin-off based on the potential of Roche-developed emactuzumab for TGCT, a debilitating orphan disease that causes joint damage and has limited clinical options.

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SynOx Raises €37m • Source: Archive

Spun out of parent company Celleron Therapeutics Ltd and armed with €37m from a series A financing, SynOx Therapeutics is advancing a cancer drug that was on the shelf at Roche Holding AG for the rare disease tenosynovial giant cell tumour (TGCT).

The drug in question is emactuzumab (RG7155), an investigational monoclonal IgG1 antibody designed to target and deplete tumor-associated macrophages in the tumor tissue

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