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Urovant’s Vibegron Flops In IBS Study

Decision on OAB Indication Awaits

 
• By Alexandra Shimmings

Another disappointment for irritable bowel syndrome therapies as Urovant Science’s vibegron fails in a Phase II trial, likely spelling the end for the investigational indication.    

Human colon
• Source: Shutterstock

Urovant Sciences, Inc.’s oral beta-3 agonist vibegron has missed its primary endpoint in a Phase IIa study in the treatment of irritable bowel syndrome (IBS) pain.

The news comes as Urovant awaits the verdict of the US Food and Drug Administration on its new drug application...

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