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Zealand’s Dasiglucagon Down But Not Out In CHI?

 
• By Alexandra Shimmings

Zealand has been hit by an unexpected Phase III failure for its glucagon analog product dasiglucagon in congenital hyperinsulinism, but all may not be lost for the indication.  

Injection and baby_1687111456_1200.jpg
• Source: Shutterstock

Zealand Pharma A/S’s first Phase III trial with dasiglucagon as a treatment for the rare pediatric disease, congenital hyperinsulinism (CHI) has met with failure, casting a shade over its prospects.

Zealand’s ambition is to create a franchise around dasiglucagon, an analog of human glucagon designed to be stable in solutions,...

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