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Roche’s Ophthalmic Bi-Specific Faricimab Still A DME Contender

Data In Wet AMD Still Awaited

 
• By Alexandra Shimmings

Initial data show non-inferiority to Eylea in diabetic macular edema with reduced frequency dosing but not superiority. Even so, market dynamics suggest it could still carve out blockbuster sales.    

diabetic macular edema • Source: Shutterstock

Top-line data for two identical Phase III studies of faricimab, Roche Holding AG’s novel bispecific antibody product for retinal diseases, suggest it is no better than Bayer AG’s Eylea but still likely to prove a thorn in the side of Novartis AG’s newcomer Beovu.

The two trials – YOSEMITE and RHINE – in a total of 1,891 patients with diabetic macula edema (DME) both...

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