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Rhythm May Have Data To Add Indication To Imcivree’s Label

 
• By Joseph Haas

Drug already approved for multiple rare genetic disorders of obesity shows significant weight-loss reduction in Bardet-Beidl syndrome, but not in the smaller indication of Alström syndrome.

Rhythm's latest data could lead to an important label expansion

Rhythm Pharmaceuticals, Inc., focused on rare genetic diseases of obesity, unveiled more Phase III data for its lead candidate setmelanotide on 22 December, but the results were somewhat mixed because the study enrolled patients with two different MCR4-mediated diseases and most of the positive data, including for the primary endpoint, came from one disease population.

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