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While Amgen Sees Success For Two Growth Drivers, Headwinds Remain

Breakthrough Drugs Sotorasib, Tezepelumab Edge Closer To Market

 
• By Mandy Jackson

Scrip discussed key wins for sotorasib in lung cancer and tezepelumab in asthma with Amgen executives Murdo Gordon and David Reese, but COVID-19 and other challenges are looming.

Amgen sign at biopharmaceutical company campus in Silicon Valley, biotech company headquartered in Thousand Oaks - South San Francisco, CA, USA - 2020
Amgen's sotorasib is filed with the US FDA; tezepelumab is being prepared for filings • Source: Shutterstock

Amgen, Inc. entered 2021 with two new high-profile potential additions to its commercial portfolio – sotorasib for non-small cell lung cancer patients with KRAS G12C mutations and tezepelumab for severe asthma. But while Amgen executive vice presidents David Reese and Murdo Gordon are looking forward to bringing these therapies to market in the next year or so, COVID-19 impacts on sales and competitive pressures remain near-term headwinds to the company’s growth.

Scrip spoke with Reese, EVP of research and development, and Gordon, EVP of global commercial operations, about pivotal data, filing plans and commercial preparations for sotorasib and tezepelumab, both of which have breakthrough therapy designations from the US Food and Drug Administration for their initial indications

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