Pfizer Says JAKs Have Their Place Despite Xeljanz Safety Issues

Management said it remains confident in Xeljanz and believes next-generation JAKs will be sufficiently differentiated. Pfizer's Vyndaqel and biosimilars businesses emerged as new blockbusters.

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Pfizer says its JAK growth pillar remains strong • Source: Shutterstock

Pfizer Inc. management said it remains optimistic about the commercial potential of its JAK inhibitor portfolio despite renewed safety concerns that have emerged with its blockbuster rheumatoid arthritis drug Xeljanz (tofacitinib).

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