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Lilly’s Tirzepatide Effective, But Tolerability Still A Limitation

Drug Reduces A1C, Weight In Diabetes

 
• By Alaric DeArment

Tirzepatide’s efficacy seems to outweigh tolerability concerns at the lower doses, but the highest dose may be relegated to niche use.

Diabetes
Tolerability could remain a limitation for Lilly's tirzepatide despite positive Phase III efficacy data • Source: Shutterstock

The efficacy of Eli Lilly and Company’s tirzepatide appears likely to outweigh concerns about adverse events and treatment discontinuations in patients taking it for type 2 diabetes on top of insulin products, at least at the lower dose levels.

The Indianapolis-based drug maker announced positive data from the Phase III SURPASS-3 and SURPASS-5 clinical trials on 17 February

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