Lilly Broadens Its CNS Reach With Rigel RIPK1 Deal

Joins Sanofi And Denali In Class

The RIPK1 inhibitor class has yet to reach proof-of-concept, but could bolster Lilly’s dogged pursuit of progress in Alzheimer’s disease.

Eli Lilly logo sign atop Lilly Biotechnology Center
Lilly has maintained neurodegeneration investment despite multiple failures - but new targets are bringing renewed hope of progress.

Eli Lilly has signed a deal to co-develop and commercialize Rigel Pharmaceuticals’ R552, a novel drug with promise against a range of immunological and neurodegenerative diseases.

Rigel will receive an upfront cash payment of $125m, with the potential for up to $835m in future milestones

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