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Pfizer Embraces Biotech-Like Speed To Advance BCMA Bispecific

Phase II Pivotal Trial Under Way For Elranatamab In Multiple Myeloma

 
• By Mandy Jackson

Chris Boshoff, Pfizer Oncology chief development officer, said lessons from the rapid pace of the company’s COVID-19 vaccine program are being applied to elranatamab and other cancer therapies.

3D Rendering of abstract highway path through digital binary towers in city
Pfizer is advancing its oncology pipeline with biotech-like speed and pharma scale • Source: Shutterstock

Pfizer Inc. has promised 25 new therapies by 2025 with 14 of those coming from its oncology research and development pipeline, including the bispecific antibody elranatamab for multiple myeloma. The B-cell maturation antigen (BCMA)-targeting, T-cell-recruiting therapy moved into a pivotal Phase II clinical trial within months of generating positive response rates in a Phase I trial, in line with Pfizer’s new focus on rapidly delivering breakthrough therapies to patients.

Pfizer Oncology chief development officer Chris Boshoff told Scrip that the process of developing and bringing a COVID-19 vaccine to...

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