Many classical disease targets have a number of therapeutic drug options, like the statins and the H2-receptor antagonists. Historically, pharmaceutical discovery groups have followed each other around, but there may be little comfort if a target takes a long time to invalidate.
Stock Watch: Like Moths To The Unvalidated Flame
Considering Target Validation In Light Of Novartis’s Lung Cancer Failure
Leaving the validation of a drug target until the end of Phase III studies is risky, but working on the unvalidated targets identified by others is riskier still.

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Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.
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