BMS/Bluebird Ready Abecma, First BCMA-Targeting CAR-T, For Initial Patients

REMS-Required Training And Certification Under Way

Idecabtagene vicleucel for fifth-line multiple myeloma lags GSK’s BCMA-targeting ADC Blenrep, but it is months ahead of J&J/Legend’s CAR-T. Abecma is BMS’s second CAR-T approval this year.

Man in red shirt preparing for stair run — BMS and bluebird won the race to bring a BCMA-targeting CAR-T to market, but the climb to commercial success begins now • Source: Shutterstock

Bristol Myers Squibb Company and bluebird bio are bringing to market the first chimeric antigen receptor T-cell (CAR-T) therapy targeting B-cell maturation antigen (BCMA) and the first CAR-T therapy for multiple myeloma. BMS chief commercialization officer Chris Boerner told Scrip that the initial focus of the Abecma (idecabtagene vicleucel, ide-cel) launch is working to certify the first treatment centers to administer the one-time treatment following US Food and Drug Administration approval on 26 March.

Abecma, which is under review for approval in the EU, was approved by the FDA to treat relapsed or refractory...

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