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At Last, AZ’s Imfinzi/Tremelimumab Cancer Combo Shows Survival Benefit

Could Signal First Tremelimumab Approval

 
• By Andrew McConaghie

After five years of failure in NSCLC trials, AstraZeneca’s immunotherapy combo shows survival benefits in POSEIDON.

AstraZeneca
While Tagrisso is a market leader in targeted NSCLC treatment, AZ's immuno-oncology franchise lags behind other competitors.

After years of failed trials combining cancer drugs Imfinzi (durvalumab) and tremelimumab, AstraZeneca has scored its first survival benefit success when added to chemotherapy in first-line treatment of late-stage non-small cell lung cancer .

The overall survival (OS) benefit seen in the Phase III POSEIDON study, added to the progression-free survival benefit reported in late 2019, ends a long string of late-stage failures of the immunotherapy

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Vertex Sinks On Below-Consensus Revenue, Limited Sales From New Launches

 
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Aldeyra Plans To File Reproxalap Again With New Dry Eye Symptom Data

 
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Vertex Sinks On Below-Consensus Revenue, Limited Sales From New Launches

 
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