Novartis and Molecular Partners have begun a pivotal trial of novel therapy ensovibep (MP0420) to see if it can prevent people with early-stage COVID-19 from worsening symptoms and being hospitalized.
Novartis COVID-19 Therapy Could Overcome Escape Variant Problem
Protein Therapeutic Enters Pivotal Trial
The DARPin candidate will not gain emergency approval before early 2022, but its likely ability to sustain efficacy regardless of SARS-CoV-2 mutations could be valuable as new variants emerge.

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While CAR-NKs have pivoted towards autoimmune disease, the Norwegian biotech believes its unique platform can deliver in oncology
The triple therapy improves lung function in the Phase III KALOS and LOGOS studies