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More Positive Data As Decision Day Looms For AstraZeneca Lupus Drug

Anifrolumab Improves Skin Rash And Arthritis

 
• By Kevin Grogan

Competition to GlaxoSmithKline’s Benlysta in the systemic lupus erythematosus space finally looks imminent with approval decisions on AstraZeneca's anifrolumab pending. The company has presented more data at EULAR to make its case for the first-in-class type I interferon inhibitor.

Tulip
Tulip yields more promising data • Source: Alamy

With anifrolumab under review by regulatory authorities in the US, EU and Japan, AstraZeneca PLC has presented more positive data on the therapy which could become the first treatment approved for systemic lupus erythematosus (SLE) in over a decade.

The UK drugs major has presented a post-hoc analysis of pooled data from the TULIP Phase III trials at the European Congress of Rheumatology (EULAR) showing that anifrolumab, a first-in-class type I interferon inhibitor, was consistently associated with improvements in both skin rash and arthritis

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