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Killing Targeted Bacteria With CRISPR Drugs Is SNIPR BIOME's Promise

CEO Says Danish Biotech Wants To Soon Raise $100-$150m

 
• By Sten Stovall

SNIPR BIOME aims to be the world’s top developer of CRISPR-based drugs that selectively target and kill bacteria, while leaving the rest of the patient’s microbiome intact, the biotech’s CEO tells Scrip.    

SNIPR BIOME's first candidate will target only E. coli bacteria in the gut • Source: Alamy

Denmark-based SNIPR Biome ApS has developed a CRISPR/Cas 3 approach to precisely target bacteria like E. coli to prevent infections without harming the beneficial bacteria in the patient’s microbiome and aims to test its first candidate therapy in humans during the first half of 2022, the biotech’s CEO told Scrip.

The microbiome-focused start-up has a license to patented CRISPR/Cas technology and is developing therapies to selectively eradicate target bacteria based on specific DNA sequence signatures in the bacterial genome, while...

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