Novartis Challenger To Alexion Advances In Rare Kidney Disease

Ultomiris Head-to-Head Planned

First-in-class iptacopan could help Novartis expand into kidney disease, and take on Alexion’s blockbuster rare disease franchise.

Novartis NIBR Cambridge, MA — Analysts at Jefferies think iptacopan could hit $3.6bn in peak annual sales. • Source: Alamy

Novartis has unveiled promising Phase II results for its investigational product iptacopan in IgA nephropathy (IgAN), one of several rare kidney diseases for which it could eventually become a blockbuster therapy.

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