Roughly three years into its effort to develop combination therapy addressing the various pathologies of non-alcoholic steatohepatitis, Terns Pharmaceuticals, Inc. has unveiled Phase II data demonstrating that its most advanced candidate – FXR agonist TERN-101 – offers the clinical benefits of its class with potentially a better safety and tolerability profile.
Terns Says Phase IIa Data Show Superior NASH Safety Profile In FXR Class
TERN-101 showed a superior safety and tolerability profile for lipid levels and pruritis compared to other FXR agonists in a mid-stage study. Terns is now looking to a NASH combo study with its THR beta agonist.
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