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Finance Watch: Big Bucks For T-regs In Autoimmune Diseases, Inflammation

GentiBio’s Mega-Round Follows Sonoma Bio’s $265m Financing

 
• By Mandy Jackson

GentiBio closed a $157m series A venture capital round, while clinical trial innovator Reify Health raised a $220m series C and Neurelis secured $150m. Also, IPOs slowed in August, but Adagio and Eliem grossed $309.4m and $80m, respectively, and RNA firm Greenlight will go public in a $282m SPAC deal. 

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T-cell therapies are all the rage in immuno-oncology drug development but have not gained quite the same momentum in autoimmune and inflammatory diseases – unless recent financings are a sign of things to come. GentiBio, Inc. said on 11 August that it closed a $157m series A venture capital round to fund its development of engineered regulatory T-cell (Treg) therapies for autoimmune, inflammatory, alloimmune and allergic diseases.

Boston-based GentiBio made its funding announcement a week after Sonoma Biotherapeutics revealed a $265m series B round to fund the first clinical trials for its autologous Treg therapies designed to restore immune

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