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All Over For Servier's Autism Ambitions

Neurochlore-Partnered Bumetanide Fails in Phase III

 
• By Kevin Grogan

The diuretic bumetanide had shown potential to improve the core symptoms of children and adolescents with autism in small studies but has failed to demonstrate any sign of effectiveness in two late-stage trials.

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• Source: Archive

Les Laboratoires Servierand fellow French firm Neurochlore's efforts to develop the common diuretic bumetanide as a treatment for the symptoms of autism have floundered after they unveiled disappointing late-stage results.

The partners noted that "no sign of effectiveness was observed" in two Phase III studies assessing bumetanide versus placebo in...

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