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Australian Biotech Hopes Nasal Spray Can Alter Course Of COVID-19 Spread

COPD Among Other Potential Areas

 
• By Anju Ghangurde

ENA Respiratory expects its "preventive" nasal spray, which primes innate immunity against respiratory viruses including SARS-CoV-2, to play a meaningful role in protecting at-risk populations and lowering community transmission of COVID-19. It plans to explore the potential of the broad-spectrum antiviral immunomodulator in other areas, including COPD, and wider partnering opportunities.

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ENA Hopes Self-Administered Nasal Spray Can Complement COVID-19 Vaccines • Source: Alamy

The Australian biotech company, ENA Respiratory, is progressing its fast-acting nasal spray for the prevention of COVID-19 and other respiratory viral infections and hopes to explore partnerships for the innate immune agonist, including in manufacturing, down the line.

ENA’s lead candidate, INNA-051 is a synthetic pegylated TLR2/6 agonist expected to move into two distinct Phase II trials early next year - a randomized COVID-19 post-exposure antiviral prophylaxis study across an estimated six-odd countries and an

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