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Apnimed Moves Closer To Phase III With Sleep Apnea Drug

 
• By Joseph Haas

Apnimed is going to conduct one more Phase II study in sleep apnea, mainly to assess subjective endpoint questionnaires, and then hopes to launch a Phase III program by autumn of 2022.

Woman wearing CPAP machine for sleep apnea
Apnimed hopes to develop the first drug to replace CPAP therapy in sleep apnea

Previous efforts to provide a drug therapy for obstructive sleep apnea patients have fallen short of the finish line but Apnimedsays it is getting closer to taking its daily, oral combination pill into pivotal Phase III trials after a pair of successful Phase II data readouts for AD109.

On 13 October, the Cambridge, MA-based company reported that AD109 – which combines the novel, selective antimuscarinic agent aroxybutynin with...

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Novartis has strengthened its argument that ianalumab, its BAFF-R inhibitor and ADCC-mediated B-cell depletor candidate, has PIP potential with successful topline results in two Phase III Sjögren’s syndrome trials, after recently dropping the product in hidradenitis suppurativa.

Pipeline Watch: Five Approvals And Two Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.

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Vertex’s Pain Drug Failure Adds To Investor Doubts

 
• By Andrew McConaghie

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• By Anju Ghangurde

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