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Metacrine’s Shift Means Further Attrition In FXR Agonist Class For NASH

 
• By Joseph Haas

Metacrine halts development of its FXR agonist compounds in NASH and turn its focus to inflammatory bowel disease. Firm plans Phase II ulcerative colitis study in 2022 with MET642.

Employee or Marketing teams are jointly meta Analysis of strengths, weaknesses and product. Including brainstorming to plan for cooperation
Metacrine is changing course to a focus on IBD, rather than NASH

Metacrine, Inc. will halt its non-alcoholic steatohepatitis (NASH) research and development after unveiling mixed Phase IIa data for FXR agonist MET642 in NASH patients. Now, the San Diego firm says it will move the same compound into inflammatory bowel disease (IBD), with a Phase II study in ulcerative colitis expected to begin during the first half of 2022.

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